There have been around 5,600 peer reviewed and published biometrical studies of the medical properties and components of the turmeric. It has shown to have over 600 preventive and therapeutic applications and 175 distinct beneficial physiological effects. The studies have shown that turmeric compares favorably to a number of conventional medications such as:
- Lipitor/Atorvastatin (cholesterol medicine) – the standardized preparation of curcuminoids from turmeric compared favorably to this drug (trade name Lipitor) on endothelial dysfunction, the underlying pathology of the blood vessels which drives atherosclerosis, in association with reductions in inflammation and oxidative stress in type2 diabetic patients (a study published in 2008 in the journal Drugs in R & D).
- Aspirin (blood thinner) – curcumin has prostacyclin and anti-platelet modulating effects compared to the drug which indicates that it may have value in patients who are prone to vascular thrombosis and who require anti-arthritis therapy (an in vitro and ex vivo study published in the journal Arzneimittelforschnug in 1986).
- Prozac/Fluoxetine & Imipramine (antidepressants) – curcumin compared favorably to both of the drugs which reduced the depressive behavior in animals (a study published in the journal Acta Poloniae in 2011).
- Metformin (diabetes drug) – curcumin was explored how it may be valuable in treating diabetes as it activates AMPK (the increases the glucose intake), suppressing gluconeogenic gene expression (that suppresses glucose production of the liver) in hepatoma cells. It was shown to be 500 times to 100,000 times (in the form known as tetrahydrocurcuminoids (THC) more potent than metformin in activating AMPK and its downstream target acetyl-CoA carboxylase (ACC) (a study published in the journal Biochemistry and Biophysical Research Community in 2009).
- Corticosteroids (steroid medications) – the primary polyphenol in turmeric, the saffron colored pigment (curcumin), compared favorably to steroids in the management of chronic anterior uveitis, an inflammatory eye disease (a study published in 1999 in the Journal Phototherapy Research). Curcumin compared favorably to the corticosteroid drug dexamethasone in the animal model as an alternative therapy for protecting lung transplantation-associated injury by down-regulating inflammatory genes (a study published in 2008 in Critical Care Medicine). The same drug has also been compared favorably to dexamethasone in a lung ischaemia-repurfusion injury model (a study published in Cancer Letters in 2003).
- Oxaliplatin (chemotherapy drug) – curcumin compares favorably with oxaliplatin as an antiproliferative agenet in colorectal cell lines (a study published in the International Journal of Cancer in 2007).
- Anti-inflammatory drugs – curcumin is an effective alternative to aspirin, ibuprofen, phenylbutazone, sulindac, tamoxefin, celecoxib, dexamethasone, diclofenac, indomethacin, and naproxen in exerting anti-inflammatory and anti-proliferate activity against tumor cells (a study published in the journal Oncogene in 2004).
Moreover, turmeric along with its components revealed remarkable therapeutic properties in drug resistant and multi-drug resistant cancers. Curcumin tops these drugs. There have been around 54 studies which indicate that curcumin is able to induce cell death or sensitize drug-resistant cancer cell lines to conventional treatment. There are 27 studies which showed the curcumin’s ability to induce cell death or sensitize multi-drug resistant cancel cell lines to conventional treatment. This is a strong argument for using curcumin as a drug alternative or adjuvant in cancer treatment. You may use it in lower culinary doses on daily basis. It is better than nourishing yourself rather than self-medicating.